Akkermansia

Akkermansia is in 3,000+ science publications

Akkermansia muciniphila is a type of bacteria that resides in the gut microbiota, specifically in the mucus layer of the intestines.

This bacterium has gained significant attention in recent years due to its potential role in glucose metabolism and metabolic disorders such as type 2 diabetes.

Gut microbiota also play a role in modifying bile, leading to the formation of secondary bile acids. These modified bile acids can affect your metabolism and signaling pathways.

Some secondary bile acids, such as ursodeoxycholic acid (UDCA), may have protective effects against liver diseases and gallstone formation.

If you want to cultivate the right gut flora for gallbladder health, here are some facts you need to know:

• Healthy bacteria in the gut influences the solubility of cholesterol in bile, reducing the likelihood of cholesterol crystallization and gallstone development.
• Having healthy microbiota also creates healthy bile acid metabolism.
• A healthy gut barrier prevents harmful substances from permeating your intestines and entering the bloodstream.
• Akkermansia muciniphila has been shown to maintain the integrity of the gut barrier, reducing inflammation in the body, supporting liver health and healthy bile acid metabolism.
• Akkermansia muciniphila has also been shown to play a role in reducing non-alcoholic fatty liver disease.

Active Ingredients:

Akkermansia muciniphila WB-STR-0001, 100 million AFU
Chicory Inulin, 276 mg

Other Ingredients:

Microcrystalline cellulose, hypromellose (vegetarian capsule), L-leucine, silica

Suggested Use:

Begin by taking one capsule, 2-3 times per week. Work your way up to taking one capsule per day. Expect to use at least 3-4 bottles consistently before noticing the supportive effects – for that reason, a subscription is highly recommended. For best results, keep product refrigerated. 

Note:

The images pictured here are for Pendulum's retail version of this probiotic. We carry and sell the PRO version, which you cannot access on the Pendulum website. The strength of this probiotic is the same, however the PRO version features enhanced bacterial longevity, meaning more of your probiotic will reach your gut alive! We recommend keeping this and all probiotics refrigerated for maximum benefit.

References:

Gut Akkermansia muciniphila ameliorates metabolic dysfunction-associated fatty liver disease by regulating the metabolism of L-aspartate via gut-liver axis. Lipid Biology and Metabolic Disease Research Group, School of Health and Biomedical Sciences, RMIT University, Melbourne, Australia (PubMed)

Naito Y, Uchiyama K, Takagi T. A next-generation beneficial microbe: Akkermansia muciniphila. J Clin Biochem Nutr. 2018 Jul;63(1):33-35. doi: 10.3164/jcbn.18-57. Epub 2018 Jun 20. PMID: 30087541; PMCID: PMC6064808

Zhou K. Strategies to promote abundance of Akkermansia muciniphila, an emerging probiotics in the gut, evidence from dietary intervention studies. J Funct Foods. 2017 Jun;33:194-201. doi: 10.1016/j.jff.2017.03.045. Epub 2017 Mar 29. PMID: 30416539; PMCID: PMC6223323